RecruitingEarly Phase 1Drug trialStudy to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary SyndromeThe purpose of this study is to determine if estradiol augmentation of luteinizing hormone (LH) secretion secretion (primary endpoint) and follicle-stimulating hormone (FSH) secretion (secondary endpoint) is reduced in adult women with polycystic ovary syndrome.